| Conker's Bad Fur Day | 2001 | Rare Ltd. | Nintendo 64 |
| Bloody Roar 3 | 2001 | Hudson Soft, Eighting | PlayStation 2, arcade video game machine |
| Toy Story Racer | 2001 | Traveller's Tales, Tiertex Design Studios | PlayStation, Game Boy Color |
| Fear Effect 2: Retro Helix | 2001 | Kronos Digital Entertainment | PlayStation, Microsoft Windows |
| Q133953221 | 2001 | Syscom Entertainment | PlayStation 2, PlayStation 3 |
| Severance: Blade of Darkness | 2001 | MercurySteam | Microsoft Windows |
| X-treme Express | 2001 | Syscom Entertainment | PlayStation 2, PlayStation 3 |
| Payback | 2001 | — | Classic Mac OS, Game Boy Advance, Amiga 1200, iOS, WarpOS, GP2X, Android |
| NBA Hoopz | 2001 | Eurocom | PlayStation, PlayStation 2, Dreamcast, Game Boy Color |
| Theme Park Inc | 2001 | Bullfrog Productions | Microsoft Windows |
| Iron Aces | 2001 | — | Dreamcast |
| Superchix '76 | 2001 | Driver-Inter, Ltd., Fiendish Games | Microsoft Windows |
| RuneScape | 2001 | Jagex | Microsoft Windows, macOS, Java platform, Java virtual machine, Android |
| Konung: Legends of the North | 2000 | Strategy First | Microsoft Windows |
| Noddy and the Birthday Party | 2000 | — | Game Boy Color |
| Grand Theft Auto 2 | 2000 | — | Game Boy Color |
| Vanishing Point | 2000 | — | PlayStation, Dreamcast |
| Project I.G.I. | 2000 | Innerloop Studios | Microsoft Windows |
| Woody Woodpecker Racing | 2000 | — | PlayStation, Microsoft Windows |
| The Mummy | 2000 | Rebellion Developments | PlayStation, Microsoft Windows |
| Robot Wars: Metal Mayhem | 2000 | Tiertex Design Studios | Game Boy Color |
| Disney's Aladdin in Nasira's Revenge | 2000 | Argonaut Games | PlayStation, Microsoft Windows |
| Noddy's Magic Adventure | 2000 | BBC Multimedia | PlayStation |
| RC Revenge Pro | 2000 | Acclaim Entertainment | PlayStation 2 |
| Road Champs: BXS Stunt Biking | 2000 | HotGen | Game Boy Color |
| Cossacks: European Wars | 2000 | GSC Game World | Microsoft Windows |
| Orbiter | 2000 | — | Microsoft Windows |
| Star Wars Episode I: Obi-Wan's Adventures | 2000 | HotGen | Game Boy Color |
| Tom and Jerry in House Trap | 2000 | Warthog Games | PlayStation |
| Airforce Delta | 2000 | — | Game Boy Color |
| 007 Racing | 2000 | Eutechnyx | PlayStation |
| Banjo-Tooie | 2000 | Rare Ltd. | Nintendo 64, Xbox 360 |
| Blade | 2000 | — | PlayStation |
| Hitman: Codename 47 | 2000 | IO Interactive | Microsoft Windows |
| Tomb Raider: Chronicles | 2000 | Core Design | PlayStation, Classic Mac OS, Microsoft Windows, Dreamcast |
| Driver 2 | 2000 | Ubisoft Reflections | PlayStation |
| Mickey's Speedway USA | 2000 | Rare Ltd. | Nintendo 64 |
| The Emperor's New Groove | 2000 | Argonaut Games | PlayStation, Microsoft Windows, Game Boy Color |
| International Cue Club | 2000 | Takara | PlayStation 2, Microsoft Windows |
| Europa Universalis: Crown of the North | 2000 | Paradox Interactive | Microsoft Windows |
| Michael Owen's WLS 2000 | 2000 | Silicon Dreams Studios | Nintendo 64 |
| Action Man: Operation Extreme | 2000 | Blitz Games | PlayStation |
| Disney's 102 Dalmatians: Puppies to the Rescue | 2000 | Crystal Dynamics | PlayStation, Microsoft Windows, Dreamcast |
| Crash Bash | 2000 | Eurocom | PlayStation, PlayStation Portable |
| Sheep | 2000 | Mind's Eye Productions | PlayStation, Microsoft Windows, macOS, Game Boy Advance |
| Chicken Run | 2000 | Blitz Games | PlayStation, Microsoft Windows, Dreamcast, Game Boy Color |
| Metropolis Street Racer | 2000 | Bizarre Creations | Dreamcast |
| Aqua Aqua | 2000 | — | PlayStation 2 |
| Arthur! Ready to Race | 2000 | Mattel | PlayStation |
| The World Is Not Enough | 2000 | Eurocom | Nintendo 64 |
| Pac-Man: Adventures in Time | 2000 | — | Microsoft Windows |
| Rugrats in Paris: The Movie | 2000 | Avalanche Software | PlayStation, Microsoft Windows, Nintendo 64 |
| Championship Manager: Season 00/01 | 2000 | Sports Interactive | Microsoft Windows |
| Midnight Club: Street Racing | 2000 | Rockstar San Diego | PlayStation 2, Game Boy Advance |
| Smuggler's Run | 2000 | Rebellion Developments, Rockstar San Diego | PlayStation 2, Nintendo GameCube, Game Boy Advance |
| TimeSplitters | 2000 | Crytek UK | PlayStation 2 |
| Medal of Honor: Underground | 2000 | Dreamworks Interactive | PlayStation, Game Boy Advance |
| Europa Universalis | 2000 | Paradox Interactive, Development Studio | Commodore Amiga, Microsoft Windows |
| Muppet Monster Adventure | 2000 | Magenta Software | PlayStation |
| F1 Manager | 2000 | Intelligent Games | Microsoft Windows |