| I am Bread | 2015 | Bossa Studios | Microsoft Windows, macOS, iOS, PlayStation 4, Android |
| I Am Fish | 2021 | Bossa Studios | Xbox One, Microsoft Windows |
| I Am Ripper | — | White Paper Games | Microsoft Windows |
| I Love Hue Too+ | 2026 | Zut Games | iOS, iPadOS |
| I, Ball | 1987 | — | ZX Spectrum, Amstrad CPC, Commodore 64 |
| I-Ninja | 2003 | Argonaut Games | PlayStation 2, Xbox, Microsoft Windows, Nintendo GameCube |
| I-War | 1998 | Particle Systems | Microsoft Windows |
| I-War | 1995 | Imagitec Design | Atari Jaguar |
| I.G.I. Origins | — | Antimatter Games | Microsoft Windows |
| I.G.I.-2: Covert Strike | 2003 | Innerloop Studios | Microsoft Windows |
| Ian Fleming's James Bond 007 in Live and Let Die: The Computer Game | 1988 | Elite Systems | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| IBomber Attack | 2012 | Cobra Mobile | Microsoft Windows, macOS, Linux |
| IBomber Defense | 2011 | Cobra Mobile | macOS |
| IBomber Defense Pacific | 2012 | Cobra Mobile | Microsoft Windows, macOS |
| ICarly | 2009 | Blitz Games | Nintendo DS, Wii |
| ICBM | 2020 | — | Microsoft Windows |
| Ice Age 2: The Meltdown | 2006 | Eurocom | PlayStation 2, Xbox, Microsoft Windows, Nintendo DS, Nintendo GameCube, Game Boy Advance, Wii |
| Ice Age: Dawn of the Dinosaurs | 2009 | Eurocom | PlayStation 2, PlayStation 3, Microsoft Windows, Xbox 360, Wii |
| Ice Age: Scrat's Nutty Adventure | 2019 | Blue Sky Studios | Xbox One, Microsoft Windows, Nintendo Switch, PlayStation 4 |
| Ice Breaker | 2009 | — | Microsoft Windows, iOS |
| Ice Palace | 1985 | Aackosoft | Commodore 64 |
| Icebreaker: A Viking Voyage | 2013 | Nitrome | iOS, Android |
| Icicle Works | 1985 | — | Commodore 16, ZX Spectrum, Commodore Plus/4, Commodore 64 |
| ID | 1986 | — | ZX Spectrum |
| Ignition | 1997 | Unique Development Studios | Microsoft Windows, macOS, DOS, Linux |
| Igor: The Game | 2008 | Santa Cruz Games | Microsoft Windows, Wii |
| IGP Manager | 2011 | IGP Games | iOS, web browser, iPadOS, Android |
| Illyriad | 2010 | — | web browser |
| Imagination - Online Board game | 2020 | Creobit | Microsoft Windows |
| Imhotep | 1985 | Ultimate Play the Game | Commodore 64 |
| Imogen | 1986 | Micro Power | BBC Micro |
| Imp of the Sun | 2022 | Sunwolf Entertainment | Xbox One, Microsoft Windows, Nintendo Switch, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| Impact Winter | 2017 | — | Microsoft Windows, macOS, PlayStation 4 |
| Impact! | 1987 | — | Commodore Amiga |
| Imperial Glory | 2006 | Pyro Studios | Microsoft Windows, macOS |
| Imperium | 1990 | Electronic Arts | Commodore Amiga, DOS, Atari ST |
| Impossamole | 1990 | Core Design | Commodore Amiga, TurboGrafx-16, Microsoft Windows, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Impossible Mission | 2007 | System 3 | PlayStation 2, Nintendo DS, PlayStation Portable, Nintendo Switch, Wii |
| In Cold Blood | 2000 | Revolution Software | PlayStation, Microsoft Windows |
| In Sink | 2024 | — | Microsoft Windows |
| Incoming | 1998 | Rage Games | Microsoft Windows, Dreamcast, arcade video game machine |
| Incoming Forces | 2002 | Rage Games | Microsoft Windows |
| Incredible Shrinking Sphere | 1989 | — | ZX Spectrum, Commodore 64 |
| Independence War 2: Edge of Chaos | 2001 | Particle Systems | Microsoft Windows |
| Indiana Jones and the Fate of Atlantis: The Action Game | 1992 | — | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Indiana Jones and the Infernal Machine | 1999 | Lucasfilm Games | Microsoft Windows, Nintendo 64 |
| Indiana Jones and the Last Crusade | 1991 | Taito | Nintendo Entertainment System |
| Indiana Jones and the Last Crusade: The Action Game | 1989 | Tiertex Design Studios | Commodore Amiga, Sega Genesis/Mega Drive, DOS, Nintendo Entertainment System, Sega Master System, ZX Spectrum, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| Indoor Sports World | 2013 | Super Icon | PlayStation Vita |
| IndyCar Racing | 1993 | Papyrus Design Group | DOS |
| IndyCar Series | 2003 | Codemasters | PlayStation 2, Xbox, Microsoft Windows |
| IndyCar Series 2005 | — | — | PlayStation 2, Xbox, Microsoft Windows |
| Inertial Drift | 2020 | — | Xbox One, Microsoft Windows, Nintendo Switch, PlayStation 4 |
| Infection: Humanity's Last Gasp | 2016 | — | Microsoft Windows, macOS |
| Inferno | 1994 | Digital Image Design | DOS |
| Inferno Pool | 2008 | Dark Energy Digital | PlayStation 3, Xbox 360, iOS |
| Infestation | 1990 | — | Commodore Amiga, DOS, FM Towns, Atari ST |
| Infiltrator | 1985 | Aackosoft, Gray Matter Inc. | Microsoft Windows, Nintendo Entertainment System, Apple II series, ZX Spectrum, Atari 8-bit family, MS-DOS, Amstrad CPC, Commodore 64 |
| Infinitesimals | 2026 | — | Microsoft Windows, PlayStation 5, Xbox Series X and Series S |
| Infinity Field | — | Electronic Arts | iOS |
| Ingrid's Back | 1988 | Level 9 Computing | DOS, ZX Spectrum, Amstrad CPC, Amstrad PCW, MSX |
| INKS. | 2016 | State of Play | iOS, iPadOS |
| INKS.+ | 2021 | State of Play | iOS, iPadOS |
| InLiving | 2008 | — | mobile phone |
| Innocent Until Caught | 1993 | Divide By Zero | Commodore Amiga, DOS |
| Insane | 2000 | Invictus Games | Microsoft Windows |
| Insane Insects: The Inception | 2016 | — | Microsoft Windows |
| Insane Robots | 2018 | — | Microsoft Windows, macOS, PlayStation 4 |
| Insanity Fight | 1987 | Linel | Commodore Amiga, iOS, Atari ST |
| Inside Outing | 1988 | Edge Games | ZX Spectrum, Amstrad CPC, Commodore 64 |
| International 3D Tennis | 1990 | Sensible Software | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| International Cricket 2010 | 2010 | Trickstar Games | PlayStation 3, Xbox 360 |
| International Cricket Captain | 1997 | — | Microsoft Windows, iOS, Android |
| International Cricket Captain 2006: Ashes Edition | 2006 | Empire Interactive | personal computer |
| International Cricket Captain 2009: Ashes Edition | 2009 | Empire Interactive | Microsoft Windows |
| International Cricket Captain III | 2007 | Empire Interactive | Microsoft Windows |
| International Cue Club | 2000 | Takara | PlayStation 2, Microsoft Windows |
| International Karate | 1985 | System 3 | DOS, Game Boy Color, ZX Spectrum, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| International Karate + | 1987 | System 3 | Commodore Amiga, Game Boy Advance, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| International Rally Championship | 1997 | Magnetic Fields | PlayStation, Microsoft Windows |
| International Rugby Challenge | 1993 | Domark Software | Commodore Amiga, Sega Genesis/Mega Drive |
| International Soccer Challenge | 1990 | — | Commodore Amiga |
| International Space Banana | 2021 | — | Microsoft Windows |
| Interphase | 1989 | The Assembly Line | Microsoft Windows, DOS, Linux |
| Interplanetary | 2015 | — | Microsoft Windows, macOS, Linux |
| Into Oblivion | 1986 | — | Microsoft Windows, macOS, ZX Spectrum, Linux, Amstrad CPC |
| Into the Eagle's Nest | 1987 | — | DOS, ZX Spectrum, Amstrad CPC, Commodore 64 |
| Into the Restless Ruins | 2025 | Ant Workshop | Microsoft Windows, Nintendo Switch, PlayStation 5, Xbox Series X and Series S |
| Into the Slimy Mines | 2026 | Ant Workshop | Microsoft Windows, Nintendo Switch, PlayStation 5, Xbox Series X and Series S |
| Intrigue! | 1986 | — | Commodore 128, Apple II, Commodore 64 |
| Invade-a-Load | 1987 | — | Commodore 64 |
| Invader | 2002 | Xicat Interactive | Game Boy Advance |
| Invasion from Beyond | 1998 | Unique Development Studios | PlayStation |
| Invasion of the Body Snatchas! | 1984 | Simon Brattel | ZX Spectrum |
| Invincible Tiger: The Legend of Han Tao | 2009 | Blitz Arcade | PlayStation 3 |
| Ionball 2: Ionstorm | 2014 | — | Microsoft Windows |
| Iron Aces | 2001 | — | Dreamcast |
| Iron Commando | 1995 | Arcade Zone | Super Nintendo Entertainment System |
| Iron Fisticle | 2014 | — | Microsoft Windows |
| Iron Front: Liberation 1944 | 2012 | — | Microsoft Windows |
| Iron Harvest | 2020 | King Art Games | Xbox One, Microsoft Windows, PlayStation 4, PlayStation 5 |
| Iron Heart | 2019 | Creobit | Microsoft Windows |
| Iron Sea Defenders | 2016 | Creobit | Microsoft Windows |
| Iron Warriors: T-72 Tank Commander | 2004 | — | Microsoft Windows, personal computer |
| Ironcast | 2015 | Dreadbit | Xbox One, Microsoft Windows, macOS, Nintendo Switch, Linux, PlayStation 4 |
| Ironclads 2: American Civil War | 2015 | — | Microsoft Windows |
| Ironclads 2: Boshin War | 2017 | — | Microsoft Windows |
| Ironclads 2: Caroline Islands War 1885 | 2017 | — | Microsoft Windows |
| Ironclads 2: War of the Pacific | 2016 | — | Microsoft Windows |
| Ironclads: American Civil War | 2008 | — | Microsoft Windows |
| Ironclads: Anglo Russian War 1866 | 2011 | — | Microsoft Windows |
| Ironclads: Chincha Islands War 1866 | 2011 | — | Microsoft Windows |
| Ironclads: High Seas | 2009 | — | Microsoft Windows |
| Ironclads: Schleswig War 1864 | 2011 | — | Microsoft Windows |
| Ironsword: Wizards & Warriors II | 1989 | Rare Ltd. | Nintendo Entertainment System |
| Is It Wrong to Try to Shoot 'em Up Girls in a Dungeon? | 2020 | — | Microsoft Windows |
| Islamic Fun | 1999 | Innovative Minds | Microsoft Windows |
| Island Saver | 2020 | — | Microsoft Windows, Nintendo Switch |
| Island Xtreme Stunts | 2002 | Silicon Dreams Studios | PlayStation 2, Microsoft Windows |
| Islanders | 2019 | GrizzlyGames | Microsoft Windows, macOS, Nintendo Switch, Linux |
| Islanders: New Shores | 2025 | Coatsink | Microsoft Windows, Nintendo Switch, PlayStation 5, Xbox Series X and Series S |
| Isle of Swaps | 2024 | Fuzz Force | Microsoft Windows |
| It Came from the Desert | 1989 | Cinemaware | Commodore Amiga, TurboGrafx-16, DOS |
| It's Mr. Pants | 2004 | Rare Ltd. | Game Boy Advance |
| Italia 1990 | 1990 | Codemasters | Commodore Amiga, Atari ST |
| Italy 1990 | 1990 | — | DOS, ZX Spectrum, Amstrad CPC, MSX |
| Ivan 'Ironman' Stewart's Super Off Road | 1989 | Leland Corporation | Commodore Amiga, Sega Genesis/Mega Drive, DOS, Nintendo Entertainment System, Super Nintendo Entertainment System, Sega Master System, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Iwakura Aria | 2024 | Mages | Microsoft Windows, Nintendo Switch |
| Iwo Jima | 1986 | Personal Software Services | ZX Spectrum, Commodore 64 |
| IWO: Bloodbath in the Bonins | 2016 | — | Microsoft Windows, macOS |