| Revenge of the Titans | 2010 | Puppy Games | Microsoft Windows, macOS, Linux, PlayStation 4 |
| Gary Grigsby's War in the East | 2010 | 2by3 Games | Microsoft Windows |
| Fluidity | 2010 | Curve Games | Wii |
| Train Simulator: Doncaster Works Route Add-On | 2010 | Dovetail Games | Microsoft Windows |
| Nail'd | 2010 | Techland | PlayStation 3, Microsoft Windows, Xbox 360 |
| PDC World Championship Darts Pro Tour | 2010 | Rebellion Developments | PlayStation 3, Xbox 360, Wii |
| Sentinel 3: Homeworld | 2010 | — | Microsoft Windows |
| Flick Golf! | 2010 | Full Fat | iOS |
| Hot Wheels Track Attack | 2010 | Firebrand Games | Nintendo DS, Wii |
| Worms: Battle Islands | 2010 | Team17 | PlayStation Portable, Wii |
| Doctor Who: Return to Earth | 2010 | Asylum Entertainment | Wii |
| Alien Breed 3: Descent | 2010 | Team17 | Microsoft Windows, Xbox 360 |
| Create | 2010 | Electronic Arts | PlayStation 3, Microsoft Windows, macOS, Xbox 360, Wii |
| Harry Potter and the Deathly Hallows – Part 1 | 2010 | Electronic Arts | PlayStation 3, Microsoft Windows, Nintendo DS, Xbox 360, Wii |
| Need for Speed: Hot Pursuit | 2010 | Criterion Games | PlayStation 3, Microsoft Windows, Xbox 360, iOS, Windows Phone, Wii, Android |
| Doctor Who: Evacuation Earth | 2010 | — | Nintendo DS |
| SingStar Dance | 2010 | London Studio | PlayStation 3 |
| Football Manager 2011 | 2010 | Sports Interactive | Microsoft Windows, macOS, PlayStation Portable, iOS |
| Kinect Sports | 2010 | Rare Ltd. | Xbox 360 |
| Kinectimals | 2010 | Frontier Developments | Xbox 360, iOS, Windows Phone, Android |
| The Biggest Loser Challenge | 2010 | Blitz Games Studios | Wii |
| GoldenEye 007 | 2010 | Eurocom | PlayStation 3, Xbox 360, Wii |
| James Bond 007: Blood Stone | 2010 | Bizarre Creations, n-Space | PlayStation 3, Microsoft Windows, Nintendo DS, Xbox 360 |
| Bloody Good Time | 2010 | Outerlight | Microsoft Windows, Xbox 360 |
| Maximum Racing: Drag & Stock Racer | 2010 | Brain in a Jar | Wii |
| Grand Theft Auto IV: Complete Edition | 2010 | Rockstar North | PlayStation 3, Xbox One, Microsoft Windows, Xbox 360 |
| TV Superstars | 2010 | Guerrilla Cambridge | PlayStation 3 |
| Buzz!: The Ultimate Music Quiz | 2010 | Relentless Software | PlayStation 3 |
| Ash | 2010 | — | Nintendo 3DS, iOS, Android |
| Get Fit with Mel B | 2010 | Lightning Fish | PlayStation 3, Xbox 360, Wii |
| DJ Hero 2 | 2010 | Ubisoft Leamington | PlayStation 3, Xbox 360, Wii |
| SingStar Guitar | 2010 | London Studio | PlayStation 3 |
| Championship Manager 2011 | 2010 | Beautiful Game Studios | iOS |
| Dead Space Ignition | 2010 | Sumo Digital | PlayStation 3, Microsoft Windows, Xbox 360 |
| A New Beginning | 2010 | Daedalic Entertainment | Microsoft Windows, macOS, iOS |
| The Shoot | 2010 | Cohort Studios | PlayStation 3 |
| Ferrari: The Race Experience | 2010 | Eutechnyx | PlayStation 3, Wii |
| Pheasants Forever Wingshooter | 2010 | High Voltage Software | Wii |
| Enslaved: Odyssey to the West | 2010 | Ninja Theory | PlayStation 3, Microsoft Windows, Xbox 360 |
| Hydrophobia | 2010 | Dark Energy Digital | PlayStation 3, Microsoft Windows, Xbox 360 |
| Disney Sing It: Party Hits | 2010 | Zoë Mode | PlayStation 3, Wii |
| TrackMania Turbo | 2010 | Firebrand Games | Nintendo DS |
| Alien Breed 2: Assault | 2010 | Team17 | Microsoft Windows, Xbox 360 |
| F1 2010 | 2010 | Codemasters | PlayStation 3, Microsoft Windows, Xbox 360 |
| AvaGlide | 2010 | — | Xbox 360 |
| Lost Horizon | 2010 | Animation Arts | Microsoft Windows, Nintendo Switch, iOS, Android |
| Pang: Magical Michael | 2010 | Mitchell Corporation | Nintendo DS |
| Space Funeral | 2010 | Stephen Gillmurphy | Microsoft Windows |
| Train Simulator: Green & Gold HST DMU Add-On | 2010 | Dovetail Games | Microsoft Windows |
| Start the Party! | 2010 | Supermassive Games | PlayStation 3 |
| The Lord of the Rings: Aragorn's Quest | 2010 | Traveller's Tales | PlayStation 2, PlayStation 3, Nintendo DS, PlayStation Portable, Wii |
| Bumps | 2010 | — | Microsoft Windows, iOS |
| Zombie Pirates | 2010 | — | Microsoft Windows |
| Decisive Campaigns: The Blitzkrieg from Warsaw to Paris | 2010 | VR Designs | Microsoft Windows |
| Worms Reloaded | 2010 | Team17 | Microsoft Windows, macOS, Linux |
| Grease | 2010 | Zoë Mode | Nintendo DS, Wii |
| Lara Croft and the Guardian of Light | 2010 | Crystal Dynamics | PlayStation 3, Microsoft Windows, PlayStation Portable, Xbox 360, iOS, BlackBerry PlayBook, Android |
| Kane & Lynch 2: Dog Days | 2010 | IO Interactive | PlayStation 3, Microsoft Windows, Xbox 360 |
| Monsteca Corral | 2010 | Onteca (United Kingdom) | Wii |
| Quell | 2010 | — | Microsoft Windows, iOS, Android |