| Surgeon Simulator 2 | 2021 | Bossa Studios | Microsoft Windows |
| Jumanji: The Curse Returns | 2021 | Marmalade Game Studio | Microsoft Windows, Nintendo Switch |
| Cute Bite | 2021 | Hanako Games | Microsoft Windows, Linux |
| Tormented Souls | 2021 | — | Microsoft Windows, Nintendo Switch, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| Murder Mystery Machine | 2021 | Blazing Griffin | Microsoft Windows, PlayStation 4 |
| Ki11er Clutter | 2021 | Puzzles By Joe | Microsoft Windows |
| King's Bounty II | 2021 | 1C Company | Xbox One, Microsoft Windows, personal computer, Nintendo Switch, PlayStation 4 |
| Recompile | 2021 | Phigames | Microsoft Windows, PlayStation 5, Xbox Series X and Series S |
| Zool Redimensioned | 2021 | — | Microsoft Windows, PlayStation 4 |
| Emergency Crew Volcano Eruption | 2021 | GameOn Production | Microsoft Windows, PlayStation 4 |
| Greak: Memories of Azur | 2021 | — | Microsoft Windows, Nintendo Switch, Nintendo 3DS, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| 1001 Jigsaw Detective | 2021 | Somer Games | Microsoft Windows |
| PAW Patrol The Movie: Adventure City Calls | 2021 | Drakhar Studio | Microsoft Windows, Nintendo Switch, PlayStation 4 |
| Cooking Trip New Challenge | 2021 | GameOn Production | Microsoft Windows |
| Lawn Mowing Simulator | 2021 | Skyhook Games Studio | Microsoft Windows, PlayStation 4 |
| Super Leap Day | 2021 | Nitrome | macOS, tvOS, iOS, iPadOS |
| Detonation Racing | 2021 | Electric Square | macOS, tvOS, iOS, iPadOS |
| No Longer Home | 2021 | Humble Grove | Xbox One, Microsoft Windows, macOS, Nintendo Switch, Linux, Xbox Series X and Series S |
| Jewel Match Origins - Palais Imperial Collector's Edition | 2021 | Suricate Software | Microsoft Windows |
| The Ascent | 2021 | Neon Giant | Xbox One, Microsoft Windows, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| Get Packed: Fully Loaded | 2021 | — | Microsoft Windows |
| Train Simulator: Southwestern Expressways: Reading - Exeter Route Add-On | 2021 | Just Trains | Microsoft Windows |
| Mystery Solitaire Grimm's Tales 3 | 2021 | Somer Games | Microsoft Windows |
| Warhammer 40,000: Battlesector | 2021 | Black Lab Games | Xbox One, Microsoft Windows, PlayStation 4, Xbox Series X and Series S |
| Death's Door | 2021 | Acid Nerve | Xbox One, Microsoft Windows, Nintendo Switch, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| Fallen Knight | 2021 | — | Microsoft Windows, PlayStation 4 |
| Griddlers Beach Season | 2021 | Creobit | Microsoft Windows |
| F1 2021 | 2021 | Codemasters | Xbox One, Microsoft Windows, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| Fill and Cross Trick or Treat | 2021 | Creobit | Microsoft Windows |
| Halloween Patchwork Trick or Treat | 2021 | Creobit | Microsoft Windows |
| TS Marketplace: London - Brighton Reigate Expansion Add-On | 2021 | Rivet Games | Microsoft Windows |
| Total War: Warhammer II - The Silence & The Fury | 2021 | Feral Interactive | Microsoft Windows, macOS, Linux |
| Griddlers TED and PET 2 | 2021 | Somer Games | Microsoft Windows |
| Horatio Goes Snowboarding | 2021 | Eastasiasoft, Infinite State Games | Xbox One, Microsoft Windows, Nintendo Switch, PlayStation 4, PlayStation 5, Xbox Series X and Series S |
| Fill and Cross Pirate Riddles 2 | 2021 | Creobit | Microsoft Windows |
| Panzer Corps 2: Axis Operations - 1942 | 2021 | Flashback Games | Microsoft Windows |
| Sniper Elite VR | 2021 | Rebellion Developments | Microsoft Windows, PlayStation 4 |
| 1001 Jigsaw: Earth Chronicles 5 | 2021 | Creobit | Microsoft Windows |
| Alice's Jigsaw Time Travel 2 | 2021 | Somer Games | Microsoft Windows |
| 1001 Jigsaw: Legends of Mystery 2 | 2021 | Somer Games | Microsoft Windows |
| Fill and Cross Pirate Riddles | 2021 | Creobit | Microsoft Windows |
| 1001 Jigsaw: Earth Chronicles 4 | 2021 | Creobit | Microsoft Windows |
| INKS.+ | 2021 | State of Play | iOS, iPadOS |
| Train Simulator: Tehachapi Pass: Mojave - Bakersfield Route Add-On | 2021 | Dovetail Games | Microsoft Windows |
| Retro Goal | 2021 | New Star Games | Nintendo Switch, iOS, iPadOS, Android |
| Planet Zoo: Africa Pack | 2021 | Frontier Developments | Microsoft Windows |
| Super Magbot | 2021 | — | Microsoft Windows |
| 7 Years From Now | 2021 | — | Microsoft Windows, Nintendo Switch |
| Train Simulator: Tauernbahn: Schwarzach-Sankt Veit - Spittal an der Drau Route Add-On | 2021 | RSSLO | Microsoft Windows |
| Valor & Victory | 2021 | Yobowargames | Microsoft Windows |
| Prison Architect: Second Chances | 2021 | Introversion Software, Double Eleven | Microsoft Windows, macOS, Nintendo Switch, Linux, iOS, PlayStation 4 |
| Train Simulator: Southern Pacific U33C Loco Add-On | 2021 | Digital Train Model | Microsoft Windows |
| Mystery Solitaire Powerful Alchemist | 2021 | Somer Games | Microsoft Windows |
| Fuzz Force: Spook Squad | 2021 | Fuzz Force | Microsoft Windows |
| The Last Kids On Earth and the Staff of Doom | 2021 | Stage Clear Studios | Microsoft Windows, Nintendo Switch |
| Train Simulator: South Devon Main Line: Highbridge and Burnham - Plymouth Route Add-On | 2021 | Just Trains | Microsoft Windows |
| Hokko Life | 2021 | Wonderscope | Xbox One, Microsoft Windows, Nintendo Switch, PlayStation 4, Xbox Series X and Series S |
| Overboard! | 2021 | Inkle | Microsoft Windows, macOS, Nintendo Switch, iOS |
| DreamWorks Spirit Lucky's Big Adventure | 2021 | A Heartful of Games | Microsoft Windows, PlayStation 4 |
| Mahjong Gold 2. Pirates Island | 2021 | Creobit | Microsoft Windows |