| Emlyn Hughes International Soccer | 1988 | — | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Exile | 1988 | — | Commodore Amiga, Acorn Electron, Atari ST, Amiga CD32, BBC Micro, Commodore 64 |
| F-16 Combat Pilot | 1988 | — | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Fish! | 1988 | Magnetic Scrolls | Commodore Amiga, DOS, ZX Spectrum, Acorn Archimedes, Amstrad PCW, Atari ST, Commodore 64 |
| Fusion | 1988 | Bullfrog Productions | Commodore Amiga, Atari ST |
| Gamma Strike | 1988 | — | ZX Spectrum, Amstrad CPC |
| Garfield: Big Fat Hairy Deal | 1988 | Edge Games | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Hallax | 1988 | — | Commodore 64 |
| Hawkeye | 1988 | Boys Without Brains | Commodore Amiga, Amiga 1200, Atari ST, Commodore 64 |
| Heroes of the Lance | 1988 | U.S. Gold | Commodore Amiga, NEC PC-8800 series, DOS, Nintendo Entertainment System, NEC PC-9800 series, Sega Master System, ZX Spectrum, Amstrad CPC, FM Towns, Atari ST, MSX, Commodore 64 |
| Hoppin' Mad | 1988 | — | ZX Spectrum, Amstrad CPC, Commodore 64 |
| HotShot | 1988 | — | DOS, ZX Spectrum, Amstrad CPC, Commodore 64 |
| Ian Fleming's James Bond 007 in Live and Let Die: The Computer Game | 1988 | Elite Systems | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Ingrid's Back | 1988 | Level 9 Computing | DOS, ZX Spectrum, Amstrad CPC, Amstrad PCW, MSX |
| Inside Outing | 1988 | Edge Games | ZX Spectrum, Amstrad CPC, Commodore 64 |
| Kane 2 | 1988 | — | Commodore 64 |
| Lancelot | 1988 | Level 9 Computing | Commodore Amiga, Classic Mac OS, DOS, ZX Spectrum, Amstrad CPC, Amstrad PCW, Atari ST, BBC Micro, MSX, Commodore 64 |
| Laser Squad | 1988 | Mythos Games | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| Last Ninja 2 | 1988 | System 3 | Commodore Amiga, DOS, Nintendo Entertainment System, ZX Spectrum, Acorn Archimedes, Commodore 64 |
| Lombard RAC Rally | 1988 | — | Commodore Amiga, DOS, Atari ST |
| Magic Johnson's Fast Break | 1988 | Arcadia Systems | DOS, Nintendo Entertainment System, ZX Spectrum, Amstrad CPC, Commodore 64 |
| Major Motion | 1988 | — | Commodore Amiga, Atari ST |
| Menace | 1988 | Rockstar North | Commodore Amiga, DOS, Atari ST, Commodore 64 |
| Mickey Mouse: The Computer Game | 1988 | Gremlin Interactive | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Microprose Soccer | 1988 | Sensible Software | DOS, ZX Spectrum, Amstrad CPC, Commodore 64 |
| Mindfighter | 1988 | — | DOS, ZX Spectrum, Amstrad CPC, Amstrad PCW |
| Morpheus | 1988 | Graftgold | Commodore 64 |
| Netherworld | 1988 | Jukka Tapanimäki | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Obliterator | 1988 | David Whittaker | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST |
| Ode to Ramon 1 | 1988 | Team Hoi | Amiga 1200 |
| Panther | 1988 | — | Commodore 64 |
| People from Sirius | 1988 | — | ZX Spectrum |
| Pipeline | 1988 | — | BBC Micro |
| Q105672438 | 1988 | — | Amstrad CPC |
| Q118113977 | 1988 | — | Amstrad CPC |
| Q125531214 | 1988 | — | Amstrad CPC |
| Ragnov | 1988 | Team Hoi | Commodore Amiga, Amiga 1200 |
| Rex | 1988 | — | ZX Spectrum, Amstrad CPC |
| Rimrunner | 1988 | — | Commodore 64 |
| RoboCop | 1988 | Data East, Nichibutsu | DOS, Nintendo Entertainment System, Game Boy, arcade video game machine, ZX Spectrum, Amiga 1200, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| Savage | 1988 | Acclaim Studios London | Microsoft Windows, DOS, ZX Spectrum, Linux, Amstrad CPC, Commodore 64 |
| Scrabble | 1988 | — | Commodore Amiga, Classic Mac OS, iOS |
| Slayer | 1988 | — | Commodore Amiga |
| Slaygon | 1988 | — | Commodore Amiga, Atari ST |
| Speedball | 1988 | The Bitmap Brothers | Commodore Amiga, PlayStation, Game Boy, Game Boy Advance, Acorn Archimedes, Xbox 360, Commodore 64 |
| Spycat | 1988 | — | Acorn Electron |
| Star Wars: Droids | 1988 | Binary Design | ZX Spectrum, Amstrad CPC, Commodore 64 |
| Starglider 2 | 1988 | Argonaut Games | Classic Mac OS, DOS, ZX Spectrum |
| Stargoose | 1988 | — | Commodore Amiga, DOS, Atari ST |
| Starring Charlie Chaplin | 1988 | Canvas Software | DOS, ZX Spectrum, Amstrad CPC |
| Super Trolley | 1988 | — | ZX Spectrum, Amstrad CPC, MSX, Commodore 64 |
| Tanglewood | 1988 | Microdeal | Commodore Amiga, Dragon 32/64, TRS-80, Atari ST |
| Target: Renegade | 1988 | Gary Biasillo | Nintendo Entertainment System, ZX Spectrum, Amstrad CPC, Commodore 64 |
| Techno Cop | 1988 | Gray Matter Inc. | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Commodore 64 |
| The Computer Edition of Scrabble | 1988 | — | Classic Mac OS, DOS |
| The Flintstones | 1988 | Krisalis Software | Commodore Amiga, Sega Master System, ZX Spectrum, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| The Fury | 1988 | — | Amstrad CPC, Commodore 64 |
| The Games: Summer Edition | 1988 | Epyx | Commodore Amiga, DOS, Apple II series, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| The Muncher | 1988 | Krome Studios Melbourne | ZX Spectrum, Commodore 64 |
| The Plot | 1988 | Odin Computer Graphics | ZX Spectrum, Amstrad CPC |