| Captive | 1990 | Mindscape | Commodore Amiga, DOS, Atari ST |
| CarVup | 1990 | Core Design | Commodore Amiga |
| Castle Master | 1990 | Incentive Software | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Chess Simulator | 1990 | Oxford Softworks | Commodore Amiga, MS-DOS, Atari ST |
| Chocks Away | 1990 | — | Acorn Archimedes |
| Clive Barker's Nightbreed: The Interactive Movie | 1990 | — | DOS |
| Cloud Kingdoms | 1990 | — | Atari ST, Commodore 64 |
| Conflict: Middle East Political Simulator | 1990 | — | DOS |
| Corporation | 1990 | The Galleon Group | Commodore Amiga, Sega Genesis/Mega Drive, DOS, Atari ST |
| Creatures | 1990 | Apex Computer Productions | Commodore Amiga, Atari ST, Commodore 64 |
| Dan Dare III: The Escape | 1990 | Acclaim Studios London | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Days of Thunder | 1990 | Krome Studios Melbourne, Argonaut Games, Creative Materials, Tiertex Design Studios | Commodore Amiga, DOS, Nintendo Entertainment System, Game Boy, ZX Spectrum, iOS, Atari ST, Commodore 64 |
| Deathbots | 1990 | Odyssey Software | Commodore Amiga, Nintendo Entertainment System |
| Deliverance: Stormlord II | 1990 | Hewson Consultants | ZX Spectrum, Amstrad CPC, Commodore 64 |
| Dragon Lord | 1990 | — | Commodore Amiga, DOS, Atari ST |
| E-Motion | 1990 | The Assembly Line | Commodore Amiga, DOS, Game Boy, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Earth Shaker | 1990 | — | ZX Spectrum |
| Elvira: Mistress of the Dark | 1990 | Adventure Soft | Commodore Amiga, DOS, Atari ST, Commodore 64 |
| European Superleague | 1990 | — | DOS, ZX Spectrum, Amstrad CPC |
| Extase | 1990 | Cryo Interactive | DOS |
| Flight of the Intruder | 1990 | Rowan Software | Commodore Amiga, DOS, Nintendo Entertainment System, Atari ST |
| Flimbo's Quest | 1990 | Euphoria, System 3 | Commodore Amiga, Amiga 1000, Amstrad CPC, Atari ST, Commodore 64 |
| Flood | 1990 | Bullfrog Productions | Commodore Amiga, Atari ST |
| Football Champ | 1990 | Taito | Commodore Amiga, Super Nintendo Entertainment System, arcade video game machine, Atari ST, Commodore 64 |
| Gazza II | 1990 | Empire Interactive | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Gremlins 2: The New Batch | 1990 | — | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, MSX, Commodore 64 |
| Hammerfist | 1990 | — | Commodore Amiga, ZX Spectrum, Atari ST, Commodore 64 |
| Hollywood Collection | 1990 | — | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Horror Zombies from the Crypt | 1990 | — | DOS |
| Humbug | 1990 | Graham Cluley | DOS |
| Hyperball | 1990 | — | Acorn Electron |
| Imperium | 1990 | Electronic Arts | Commodore Amiga, DOS, Atari ST |
| Impossamole | 1990 | Core Design | Commodore Amiga, TurboGrafx-16, Microsoft Windows, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Infestation | 1990 | — | Commodore Amiga, DOS, FM Towns, Atari ST |
| International 3D Tennis | 1990 | Sensible Software | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| International Soccer Challenge | 1990 | — | Commodore Amiga |
| Italia 1990 | 1990 | Codemasters | Commodore Amiga, Atari ST |
| Italy 1990 | 1990 | — | DOS, ZX Spectrum, Amstrad CPC, MSX |
| James Pond: Underwater Agent | 1990 | — | Commodore Amiga, Sega Genesis/Mega Drive, Acorn Archimedes, Atari ST |
| Judge Dredd | 1990 | — | Commodore Amiga, ZX Spectrum, Atari ST, Commodore 64 |
| Kenny Dalglish Soccer Match | 1990 | Impressions Games | ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Kentucky Racing | 1990 | Bizarre Developments | ZX Spectrum, Amstrad CPC, Commodore 64 |
| Kid Gloves | 1990 | — | Commodore Amiga, Atari ST |
| Leavin' Teramis | 1990 | Thalion Software | Commodore Amiga, Atari ST |
| Loopz | 1990 | Milestone S.r.l., Audiogenic | DOS, Nintendo Entertainment System, Sharp X68000, ZX Spectrum, Amstrad CPC, Commodore 64 |
| Lost Patrol | 1990 | — | Commodore Amiga, Microsoft Windows, DOS, Atari ST |
| Lotus Esprit Turbo Challenge | 1990 | Magnetic Fields | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Mad Professor Mariarti | 1990 | Krisalis Software | Acorn Archimedes |
| Magicland Dizzy | 1990 | Big Red Software | Commodore Amiga, DOS, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Matrix Marauders | 1990 | — | Commodore Amiga, Atari ST |
| MiG-29 Fulcrum | 1990 | Simis | DOS, Acorn Archimedes |
| Monty Python's Flying Circus: The Computer Game | 1990 | Core Design | ZX Spectrum, Amstrad CPC, Commodore 64 |
| Murder! | 1990 | — | Commodore Amiga, DOS, Atari ST |
| Navy SEALS | 1990 | Ocean Software | Commodore Amiga, ZX Spectrum, Amstrad CPC, Atari ST, Commodore 64 |
| Nitro | 1990 | SCE Studio Liverpool | Commodore Amiga |
| Perplexity | 1990 | — | Acorn Electron, BBC Micro |
| Pin Bot | 1990 | Rare Ltd. | Nintendo Entertainment System |
| Player Manager | 1990 | Imagineer | Commodore Amiga, Atari ST |
| Powerband | 1990 | Gordon J. Key | Acorn Archimedes |
| Projectyle | 1990 | — | Commodore Amiga |